1. Empty the loading cavity
Before loading a new cartridge, release any unused gas from the used cartridge by pressing the button or unscrewing the applicator cap. Discard the used cartridge. Check the used filter does not remain inside the cavity.
2.Load a new cartridge
The cartridges are packed in peel-pack blisters with an assembled filter and cartridge opener included. The filters are used for protection of the applicator, the opener for puncturing the cartridge.Ensure that the loading cavity is empty of all residue. Open the peel-pack. Take out the filter/opener with the tweezers. Hold the CryoPen’s tip end pointed downward. Place the filter in the instrument and make sure that it is seated flat at the bottom of the loading cavity. The trocar of the opener should be pointed upward! Take the cartridge and put it into the cavity with the narrow side down, on top of the filter/opener device.
Gently screw the CryoPen backend onto the front end. Go to the point where you feel that the contact between the assembled filter/opener device and the cartridge is established. Now, position your hands so that the last turn will be in an uninterrupted movement. Now, rotate quickly until you feel that the end of the rotation is achieved. You may eventually hear a short hissing sound. The shorter the hiss, the better! Tighten until you feel resistance; twist it until you hear a click, and make sure you keep twisting quickly after the click until it is fully tightened.